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The medical journal The Lancet on Tuesday retracted a controversial 1998 paper that linked the measles, mumps and rubella (MMR) vaccine to autism. The study subsequently had been discredited, and last week, the lead author, Dr. Andrew Wakefield, was found to have acted unethically in conducting the research. The General Medical Council, which oversees doctors in Britain, said that “there was a biased selection of patients in The Lancet paper” and that his “conduct in this regard was dishonest and irresponsible.” The panel found that Wakefield Ugg Boots subjected some children in the study to various invasive medical procedures such as colonoscopies and MRI scans. He also paid children at his son’s birthday party to have blood drawn for research purposes, an act that “showed a callous disregard” for the “distress and pain” of the children, the panel said. After the council’s findings last week, The Lancet retracted the study and released this statement. “It has become clear that several elements of the 1998 paper by Wakefield et al. are incorrect, contrary to the findings of an earlier investigation. In particular, the claims in the original paper that children were ‘consecutively referred’ and that investigations were ‘approved’ by the local ethics committee have been proven to be false. Therefore we fully retract this paper from the published record.” Dr. Richard Horton, editor of The Lancet, said he reviewed the General Medical Council report regarding Wakefield’s conduct. “It’s the most appalling catalog Cheap Ugg and litany of some the most terrible behavior in any research and is therefore very clear that it has to be retracted,” he said. CNN was unable to directly contact Wakefield. He released this statement through a representative: “The allegations against me and against my colleagues are both unfounded and unjust and I invite anyone to examine the contents of these proceedings and come to their own conclusion. In fact, the Lancet paper does not claim to confirm a link between the MMR vaccine and autism. Research into that possible connection is still going on.” The Centers for Disease Control and Prevention praised The Lancet’s retraction, saying, “It builds on the overwhelming body of research by the world’s leading scientists that concludes there is no link between MMR vaccine and autism. We want to remind parents that vaccines are very safe and effective and they save lives. Parents who have questions about the safety of vaccines should talk to their pediatrician or their child’s health care provider.” Since its publication, Wakefield’s study has attracted many critics who argued that the work had been so flawed, it should not be regarded Wholesale Ugg Boots as scientific. Wakefield theorized that the measles vaccine caused gastrointestinal problems and that those GI problems led to autism. In his view, the virus used in the vaccine grew in the intestinal tract, leading the bowel to become porous because of inflammation. Then material seeped from the bowel into the blood, Wakefield’s theory said, affecting the nervous system and causing autism. But subsequent research has been unable to duplicate Wakefield’s findings. A September 2008 study replicated key parts of Wakefield’s original paper and found no evidence that the vaccine had a connection to either autism or GI disorders. The study, conducted at Columbia University, Massachusetts General Hospital and the CDC, also found no relationship between the timing of the vaccine and children getting GI disorders or autism. The Wakefield study has been a key piece of evidence cited by many parents who do not
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